Please review the responses below in perspective with medications that have been approved by the FDA for migraine prevention.   For example, in a study to observe the long term efficacy of Depakote for migraine prevention, only 5% had continued to use Depakote for as long as 3 years, and reported an average 66% reduction of migraine events, while 70% continue to use an NTI with excellent results.

Chart from the Depakote study:



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